Research Highlights: Multi-drug treatment regenerates African clawed frog limbs

Multi-drug treatment regenerates African clawed frog limbs Source: Murugan, N. J., Vigran, H. J., Miller, K. A., Golding, A., Pham, Q. L., Sperry, M. M., Rasmussen-Ivey, C., Kane, A. W., Kaplan, D. L., & Levin, M. (2022). Acute multidrug delivery via a wearable bioreactor facilitates long-term limb regeneration and functional recovery in adult Xenopus laevis. … Continue reading Research Highlights: Multi-drug treatment regenerates African clawed frog limbs

Research Highlights: Remaining non-resistant pathogens after an antibiotic treatment may help control the growth of the resistant type

Remaining non-resistant pathogens after an antibiotic treatment may help control the growth of the resistant type Source: Hansen E, Karslake J, Woods RJ, Read AF, Wood KB (2020) Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations. PLoS Biol 18(5): e3000713. https://doi.org/10.1371/journal.pbio.3000713

Research Highlights: Cutting the Energy Source of the Malaria Parasite Plasmodium

Original Authors: Xin Jiang, Yafei Yuan, Jian Huang, Shuo Zhang, Shuchen Luo, Nan Wang, Debing Pu, Na Zhao, Qingxuan Tang, Kunio Hirata, Xikang Yang, Yaqing Jiao, Tomoyo Sakata-Kato, Jia-Wei Wu, Chuangye Yan, Nobutaka Kato, Hang Yin, Nieng Yan Malaria is a mosquito-borne disease caused by a parasite. People with malaria often experience fever, chills, and … Continue reading Research Highlights: Cutting the Energy Source of the Malaria Parasite Plasmodium

Research Article: Genetic drift assessment of cancer cell lines in pharmacogenomic studies

Genetic drift assessment of cancer cell lines in pharmacogenomic studies Genetic variation can be linked to pharmacological response using cell line model systems, but biomedical research faces dilemma when using these cell lines due to unstable genes and misidentification. Genomic instability can influence the reproducibility of research experiments that use cancer cell lines. These issues … Continue reading Research Article: Genetic drift assessment of cancer cell lines in pharmacogenomic studies

Research Highlights: SRT1720 Experimental Drug Inhibits Bladder Cancer Development

SRT1720 Experimental Drug Inhibits Bladder Cancer Development Related Video Sources: Tan, P., Wang, M., Zhong, A. et al. SRT1720 inhibits the growth of bladder cancer in organoids and murine models through the SIRT1-HIF axis. Oncogene (2021). https://doi.org/10.1038/s41388-021-01999-9 [1] https://en.wikipedia.org/wiki/SRT-1720 [2] https://pubmed.ncbi.nlm.nih.gov/29094888 [3] https://www.cancer.gov/types/bladder [4] https://en.wikipedia.org/wiki/Organoid [5] https://pubmed.ncbi.nlm.nih.gov/24020000

Highlights: Viral Videos Made Hydroxychloroquine Trending Again But Still Not A Cure for COVID-19

There is no rigorous scientific evidence that hydroxychloroquine can cure COVID-19. Hydroxychloroquine is an anti-malarial drug used to treat autoimmune diseases, not COVID-19. Even recent studies suggest that the drug does not have substantial antiviral activity. One latest study concluded that patients hospitalized with mild-to-moderate Covid-19 using hydroxychloroquine, alone or with azithromycin, did not improve … Continue reading Highlights: Viral Videos Made Hydroxychloroquine Trending Again But Still Not A Cure for COVID-19

Research Highlights: Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia

August 13, 2020 Older patients with acute myeloid leukemia (AML) have a poor prognosis, even after treatment with a hypomethylating agent. Acute myelogenous leukemia is a cancer of the blood and bone marrow — the spongy tissue inside bones where blood cells are made. A hypomethylating agent or demethylating agent is a drug that inhibits … Continue reading Research Highlights: Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia

Research Highlights: Comparison Between Psilocybin (Magic Mushroom) and Escitalopram as an Antidepressant

Comparison Between Psilocybin (Magic Mushroom) and Escitalopram as an Antidepressant April 18, 2021 Psilocybin, also known as magic mushroom, is a compound obtained from certain types of hallucinogenic mushrooms found in Mexico, South America, and some parts of the United States.[1] Psilocybin may have antidepressant properties however, comparisons between psilocybin and known treatments for depression … Continue reading Research Highlights: Comparison Between Psilocybin (Magic Mushroom) and Escitalopram as an Antidepressant

Research Highlights: Master Regulatory Proteins of the Liver Play a Role in HBV Infection

Master Regulatory Proteins of the Liver Play a Role in HBV Infection Chronic hepatitis B virus or HBV is a DNA virus in the genus Orthohepadnavirus and causes the disease hepatitis B.[1][2][3][4] HBV also causes cancer that does not have curative treatments. HBV infection is a worldwide health issue and causes more than 800,000 deaths … Continue reading Research Highlights: Master Regulatory Proteins of the Liver Play a Role in HBV Infection