Research Highlights: Influenza Virus Infected Cells Survive Immune Response

Influenza A virus (IAV) is a seasonal pathogen with the potential to cause devastating pandemics. Type A influenza infection can be serious and cause widespread outbreaks and disease. IAV infects multiple epithelial cell subsets in the respiratory tract, eliciting damage to the lungs. Epithelial cells line the outer surfaces of organs and blood vessels throughout … Continue reading Research Highlights: Influenza Virus Infected Cells Survive Immune Response

Research Highlights: Hyperbaric Oxygen Therapy May Help Increase Cell Life and Remove Senescent Immune Cells in Older Adults

Original Article: https://doi.org/10.18632/aging.202188 As we age, physiological activities in our body decrease. Shortening of the telomere length and cellular senescence are associated with the aging process. Telomeres are repetitive DNA sequences at the end of chromosomes which serves as protection. Each cell division, the telomeres become shorter. Cells can no longer divide when the telomeres … Continue reading Research Highlights: Hyperbaric Oxygen Therapy May Help Increase Cell Life and Remove Senescent Immune Cells in Older Adults

Research Highlights: High immune cell count associated with low IQ in children with HIV

Original Article: http://doi.org/10.1186/1742-6405-11-7 The human immunodeficiency virus (HIV) is an enveloped retrovirus that contains 2 copies of a single-stranded RNA genome. HIV causes the acquired immunodeficiency syndrome (AIDS) that is the last stage of HIV disease. HIV causes neurocognitive impairment possibly by transmigration through the blood brain barrier of activated T cells and infected monocytes triggering … Continue reading Research Highlights: High immune cell count associated with low IQ in children with HIV

Research Highlights: Stem cell transplant leads to HIV remission

Research Highlights: Stem Cell Transplant Leads to HIV Remission HIV remains incurable. Only one case is reported that HIV has been cured. A patient underwent stem-cell transplant using a donor with a mutation in the CCR5 gene. CCR5 is a receptor protein that HIV use to infect a cell. Supposedly, the stem-cell transplant was performed … Continue reading Research Highlights: Stem cell transplant leads to HIV remission

Research Highlights: Butyrate Produced by Gut Microbiome Can Improve Antitumor Responses of T Cells

Butyrate Produced by Gut Microbiome Can Improve Antitumor Responses of T Cells Studies have shown that gut microbiota can regulate tumor responsiveness to chemotherapy or immunotherapy. However, the mechanism of this regulation is not clear. Researchers found that metabolites from gut microbiota can increase the effectiveness of oxaliplatin by regulating CD8+ T cell function in … Continue reading Research Highlights: Butyrate Produced by Gut Microbiome Can Improve Antitumor Responses of T Cells

Research Highlights: SARS-CoV-2 Variant More Difficult to be Killed by Immune Responses from Natural Infection or Vaccination

Research Highlights: SARS-CoV-2 Variant More Difficult to be Killed by Immune Responses from Natural Infection or Vaccination The COVID-19 virus has caused more than 2 million deaths just over a year. Vaccines are being introduced to produce immune responses against the virus. The process of viral replication is prone to nucleic acid errors which can … Continue reading Research Highlights: SARS-CoV-2 Variant More Difficult to be Killed by Immune Responses from Natural Infection or Vaccination

Research Highlights: Immune Responses Between Male and Female in COVID-19

Date Published: Aug 26, 2020 Authors: Takehiro Takahashi, Mallory K. Ellingson, Patrick Wong, Benjamin Israelow, Carolina Lucas, Jon Klein, Julio Silva, Tianyang Mao, Ji Eun Oh, Maria Tokuyama, Peiwen Lu, Arvind Venkataraman, Annsea Park, Feimei Liu, Amit Meir, Jonathan Sun, Eric Y. Wang, Arnau Casanovas-Massana, Anne L. Wyllie, Chantal B.F. Vogels, Rebecca Earnest, Sarah Lapidus, … Continue reading Research Highlights: Immune Responses Between Male and Female in COVID-19

Research Highlights: Macrophages Pick-up “Trash” from Heart Muscles

Original Article: https://doi.org/10.1016/j.cell.2020.08.031 Cardiomyocytes are the cells responsible for generating contractile force in the intact heart. Cardiomyocytes are subjected to the intense mechanical stress and metabolic demands of the beating heart. Cardiomyocytes are long-lived and rarely renewed. It is unclear whether these cardiomyocytes manage to preserve homeostasis on their own. Researchers discovered that macrophages lodged … Continue reading Research Highlights: Macrophages Pick-up “Trash” from Heart Muscles

Research Highlights: Dietary Zinc and its Association with Streptococcus pneumoniae Infection

Original Article: https://doi.org/10.1371/journal.ppat.1007957 Zinc is a nutrient that people need to stay healthy, and it is found in cells throughout the body. Zinc helps the immune system fight off invading bacteria and viruses. The body also needs zinc to make proteins and DNA, the genetic material in all cells. Human zinc deficiency increases susceptibility to … Continue reading Research Highlights: Dietary Zinc and its Association with Streptococcus pneumoniae Infection